Arizona's Frostee Rucker and Hasson Reddick, and San Francisco's Carlos Hyde have been ejected for fighting.
The teams got into a skirmish in the fourth quarter Sunday after former 49ers safety Antoine Bethea hit San Francisco quarterback C.J. Beathard late as he was sliding following a run.
The 49ers took exception to the hit and players from both teams started scuffling.
Rucker, Reddick and Hyde were all tossed from the game.
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