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Virginia Commonwealth will open the NCAA tournament in San Diego against Stephen F. Austin, which has won 28 in a row.
The Lumberjacks (31-2) won the Southland Conference tournament to earn a No. 12 seed, and their first NCAA tournament berth since 2009.
VCU (26-8) lost to Saint Joseph's in the Atlantic 10 championship on Sunday. The Rams, a fifth seed, will be making their fourth consecutive trip to the NCAA tournament. They have won at least one game in each of their first three trips, including advancing to the Final Four in 2011.
The game, to be played Friday, is part of the South Regional, where overall top seed Florida is the top seed.