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Renton, WA (SportsNetwork.com) - Seattle Seahawks middle linebacker Bobby Wagner will miss a second straight game as he continues to work through a sprained ankle.

Wagner injured himself during Seattle's Week 5 loss at Indianapolis and sat out last Sunday's 20-13 win over Tennessee as a result. The second-year pro has not practiced at all this week and was ruled out for Thursday's matchup at Arizona on the final injury report.

Offensive tackle Breno Giacomini, who underwent a knee scope in late September, and reserve running back Spencer Ware (ankle) will also not play against the Cardinals.

Defensive end Chris Clemons, who sustained a hyperextended elbow in the Tennessee game, has been listed as questionable to play. The veteran was a limited participant in Wednesday's practice after not working the previous two days.

Leading rusher Marshawn Lynch (hip) and tight end Zach Miller (hamstring) are both probable to face the Cardinals.