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Seattle, WA (Sports Network) - Russell Wilson matched a career high with four touchdowns passes and the Seattle Seahawks stifled the Jacksonville Jaguars in a 45-17 rout on Sunday at CenturyLink Field.

Wilson completed 14-of-21 passes for 202 yards and an interception, with Zach Miller and Sidney Rice each hauling in two of Wilson's touchdown tosses. Backup quarterback Tarvaris Jackson, who entered for Wilson late in the third with the game well in hand, threw for a score and ran for another.

Marshawn Lynch rushed for 69 yards on 17 carries for the Seahawks (3-0), who were coming off a 29-3 demolition of the reigning NFC champion San Francisco 49ers.

Chad Henne, making his second straight start in place of an injured Blaine Gabbert, struggled under center against Seattle's stout defense, connecting on just 18-of-38 passes for 235 yards and a pair of interceptions.

Maurice Jones-Drew carried the ball 19 times for 43 yards and a score for the Jaguars (0-3), who are off to their third 0-3 start in franchise history and first since dropping their initial four games during the 2003 campaign.

The loss spoiled the homecoming of Jacksonville head coach Gus Bradley, who had spent the last three seasons as Seattle's defensive coordinator before being hired by the Jags back in January.

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