Philadelphia, PA (Sports Network) - Saint Francis (Pa.) All-America running back Kyle Harbridge will miss the rest of the season with a knee injury, the university announced Wednesday.

The senior, from Easton, Pa., led the Red Flash in rushing last year with a school-record 1,474 yards, which ranked sixth in the FCS.

Harbridge posted a single-game school record of 346 yards rushing against Morehead State last Sept. 17. The performance ranks as the most rushing yards in Division I football in the last five seasons. His 457 all-purpose yards in that game missed the FCS record by 10 yards.

"The loss of Kyle is tough. He is a great player," coach Chris Villarrial said. "However, now we have to move on and have other players to step up. We have some very talented players who are now going to get a lot more chances and we are going to need them to respond."

The news of the loss comes just days after the Red Flash's disappointing 55-7, season-opening loss at James Madison.

Harbridge will redshirt the 2012 season and hopes to make a return in 2013.

The Sports Network