After an opening question about bringing back jobs, the debate started to grow sharply personal.
Take this, for instance from Donald Trump to Hillary Clinton: "I want you to be very happy. It's very important to me." We're guessing it's not that important.
Sparks continued to fly over jobs and trade, with Trump railing against NAFTA, which was signed by President Bill Clinton.
"I know you live in your own reality," Clinton said to Trump at one point.
After Trump blasted Clinton on the Islamic State, the Democratic nominee fired back: "Fact checkers, get to work."
She eventually suggested Trump was going to blame her for everything bad that's ever happened.
"Why not?" Trump shot back.
Not long after, they turned to emails, Trump's taxes — all the classics.
"Maybe he's not as rich as he says he is," Clinton said, when speculating why he hadn't released his taxes yet.
As for Clinton's use of an a private email system while secretary of State, Trump called it "more than a mistake."